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Potential Purine Antagonists. II. Synthesis of Some 7- and 5,7-Substituted Pyrazolo[4,3-d]pyrimidines 1

โœ Scribed by Robins, Roland K.; Furcht, Frederick W.; Grauer, Alan D.; Jones, Jesse W.


Book ID
120313203
Publisher
American Chemical Society
Year
1956
Tongue
English
Weight
617 KB
Volume
78
Category
Article
ISSN
0002-7863

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## Abstract Pyrazoloโ€[3,4โ€__d__]pyrimidineโ€4,6โ€diones **5** and pyrazolo[4,3โ€__d__]pyrimidineโ€5,7โ€diones **7** were synthesized by Curtius rearrangement of pyrazolic monoโ€esters **2** and **3** followed by heteroโ€cyclization __via__ the ureas derivatives **4** and **6** under alkaline conditions.