𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Potential prodrugs of phenelzine: N2-acetylphenelzine and N2-ethoxycarbonylphenelzine

✍ Scribed by Terry J. Danielson; Ronald T. Coutts; Glen B. Baker; Man C. Chan


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
231 KB
Volume
77
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Bis(N,N-dimethylcarbamoyloxymethyl) 2β€²,
✍ Saeed R. Khan; David Farquhar πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 197 KB

Bis(N,N-dimethylcarbamoyloxymethyl) 2', 3'-dideoxyuridine 5'-monophosphate (DlvlrddUMP) (la) was synthesized as a potential membrane-permeable prodrug of ddUMP (3). Unlike the bis(pivaloyloxymethyl) analog, I b, la was completely resistant to degradation by plasma enzymes -a property that should enh

N4-(dialkylamino)methylene derivatives o
✍ Stephen G. Kerr; Thomas I. Kalman πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 635 KB

The synthesis and physicochemical parameters of a series of N4-(N,N-dialkyl)formamidine derivatives of 2'-deoxycytidine (dCyd, 1) and arabinocytidine (ara-C, 2), as prodrug prototypes, are described. The lipophilicity of the formamidine derivatives compared to that of the parent nucleosides increase

One-Pot Syntheses of 2-N-Alkylamino-, 2-
✍ Ol'ga A. Tarasova; Ludmila V. Klyba; Vladimir Yu. Vvedensky; Nina A. Nedolya; Bo πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 353 KB πŸ‘ 2 views

A number of 2-N-alkylamino-or 2-N-phenylamino-, 2-N,N-RCH 2 CϡCLi, or the lithiated allene, tBuCH=C=CHLi, and isothiocyanate, RЈN=C=S, in tetrahydrofuran and subse-dialkylamino-, and 2-N-alkyl-N-phenylaminothiophenes have been prepared in good yields by adding a solution of quently hydrolyzing the r