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Potential of imipenem as single-agent empiric antibiotic therapy of febrile neutropenic patients with cancer

✍ Scribed by James C. Wade; Harold C. Standiford; George L. Drusano; David E. Johnson; Marcia R. Moody; Carlos I. Bustamante; Jai H. Joshi; Carlos deJongh; Stephen C. Schimpff

Book ID
115680385
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
1013 KB
Volume
78
Category
Article
ISSN
1555-7162

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πŸ“œ SIMILAR VOLUMES

Efficacy of amikacin and ticarcillin as
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✍ Faden, Howard S. ;Deshpande, Ganesh N. ;Grossi, Mauro ;Surgalla, Michael ;Etting πŸ“‚ Article πŸ“… 1981 πŸ› John Wiley and Sons 🌐 English βš– 531 KB

## Abstract Amikacin (600 mg/m^2^/day IV) and ticarcillin (12 gm/m^2^/day IV) were administered to 38 children with cancer, neutropenia (< 1,000 PMN/mm^3^), and fever (β‰₯ 38Β°C) during 46 febrile episodes. Sixty‐one percent of the children were severely neutropenic (<200 PMN/mm^3^). Febrile episodes

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## BACKGROUND. The improved efficacy of imipenem over other beta-lactam antibiotics in the treatment of febrile neutropenic patients has been attributed to its broad spectrum of activity. METHODS. A prospective, randomized, clinical trial was performed comparing vancomycin 1 g every 12 hours plus