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Potential for Pharmacokinetic Interactions Between Ambrisentan and Cyclosporine

✍ Scribed by Spence, R; Mandagere, A; Richards, D B; Magee, M H; Dufton, C; Boinpally, R

Book ID
109846007
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
204 KB
Volume
88
Category
Article
ISSN
0009-9236

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Previous reports have indicated that administration of the calcium antagonist diltiazem results in major changes in the pharmacokinetics of cyclosporin A (CyA). A new clinical trial was undertaken in 22 renal transplant patients receiving a constant dose of cyclosporin to further explore this intera