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Pharmacokinetic interactions between sirolimus and cyclosporine exacerbate renal dysfunction

✍ Scribed by H Podder; S.M Stepkowski; K Napoli; B.D Kahan

Book ID
117230475
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
52 KB
Volume
33
Category
Article
ISSN
0041-1345

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Pharmacokinetic interaction between cycl
Pharmacokinetic interaction between cyclosporin and diltiazem
✍ J. BrockmΓΆller; H.-H. Neumayer; K. Wagner; W. Weber; G. Heinemeyer; H. Kewitz; I πŸ“‚ Article πŸ“… 1990 πŸ› Springer 🌐 English βš– 683 KB

Previous reports have indicated that administration of the calcium antagonist diltiazem results in major changes in the pharmacokinetics of cyclosporin A (CyA). A new clinical trial was undertaken in 22 renal transplant patients receiving a constant dose of cyclosporin to further explore this intera