Pharmacokinetic and Pharmacoimmunodynamic Interactions Between Prednisolone and Sirolimus in Rabbits
β Scribed by Geraldine M. Ferron; William J. Jusko
- Book ID
- 110308035
- Publisher
- Springer US
- Year
- 1998
- Tongue
- English
- Weight
- 620 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0724-8741
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Arbaprostil is an orally active prostaglandin E2 analogue. It has been developed as a drug to treat ulcers induced by non-steroidal anti-inflammatory drugs. In this study, pharmacokinetic interactions between arbaprostil and aspirin were examined in humans after chronic doses of both drugs. Subjects
The protein binding characteristics of prednisone and prednisolone were determined in human and rabbit plasma and in a 4.7 per cent human serum albumin (HSA) solution. The influence of plednisolone on prednisone binding in human plasma was also examined. Prednisolone exhibited nonlinear binding and