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Potential diagnostic and prognostic values of detecting promoter hypermethylation in the serum of patients with gastric cancer

✍ Scribed by Leung, W K; To, K-F; Chu, E S H; Chan, M W Y; Bai, A H C; Ng, E K W; Chan, F K L; Sung, J J Y

Book ID: 125519147
Publisher: Nature Publishing Group
Year: 2005
Tongue: English
Weight: 133 KB
Volume: 92
Category: Article
ISSN: 0007-0920
DOI: 10.1038/sj.bjc.6602636

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## Abstract Promoter hypermethylation is an alternative mechanism of gene silencing in human cancers including gastric cancer. While intestinal metaplasia (IM) is generally regarded as a precancerous lesion of the stomach, our study examines the presence of gene promoter hypermethylation in IM of p