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O33 Promoter hypermethylation profile in tumor and serum of patients with head and squamous cell carcinoma: potential diagnostic and prognostic values

✍ Scribed by Sampaio-Goes, F.; Sato, A.; Kagohara, L.; Vettore, A.; Kowalski, L.; Carvalho, F.; Carvalho, A.L.


Book ID
118655575
Publisher
Elsevier Science
Year
2007
Weight
51 KB
Volume
2
Category
Article
ISSN
1744-7895

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Promoter hypermethylation profile of tum
✍ Muthusamy Viswanathan; Nobuo Tsuchida; Govindaswamy Shanmugam πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 French βš– 211 KB

## Abstract Aberrant promoter hypermethylation of tumor‐associated genes leading to their inactivation is a common event in many cancer types. Using a sensitive restriction‐multiplex PCR method, we studied the promoter hypermethylation profile of the __p16, p15, hMLH1, MGMT__ and __E‐cad__ genes in