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Potent inhibition of in vivo angiogenesis and tumor growth by a novel cyclooxygenase-2 inhibitor, enoic acanthoic acid

✍ Scribed by Hye Jin Jung; Joong Sup Shim; Young-Ger Suh; Young-Myeong Kim; Mayumi Ono; Ho Jeong Kwon


Book ID
108584014
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
219 KB
Volume
98
Category
Article
ISSN
1347-9032

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## Abstract ## BACKGROUND: We developed an engineered three‐dimensional (3D) tumor xenograft model of nonsmall cell lung cancer (NSCLC) in nude mice, and we used this model to evaluate a dual‐activity inhibitor of lysophosphatidic acid (LPA) biosynthesis and receptor activation. ## METHODS: Firs