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Potent inhibition of human telomerase by U-73122

โœ Scribed by Yi-Jui Chen; Wei-Yun Sheng; Pei-Rong Huang; Tzu-Chien V. Wang

Book ID
106577007
Publisher
BioMed Central
Year
2006
Tongue
English
Weight
293 KB
Volume
13
Category
Article
ISSN
1021-7770

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๐Ÿ“œ SIMILAR VOLUMES

Inhibition of Human Telomerase by 7-Deaz
Inhibition of Human Telomerase by 7-Deaza-2โ€ฒ-deoxyguanosine Nucleoside Triphosphate Analogs: Potent Inhibition by 6-Thio-7-deaza-2โ€ฒ-deoxyguanosine 5โ€ฒ-Triphosphate
โœ Terace M. Fletcher; Brian E. Cathers; K.S. Ravikumar; Blain M. Mamiya; Sean M. K ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 487 KB

We have examined analogs of the previously reported 7-deaza-2ะˆ-deoxypurine nucleoside triphosphate series of human telomerase inhibitors. Two new telomerase-inhibiting nucleotides are reported: 6-methoxy-7-deaza-2ะˆ-deoxyguanosine 5ะˆ-triphosphate (OMDG-TP) and 6-thio-7-deaza-2ะˆ-deoxyguanosine 5ะˆ-trip