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Telomerase inhibition by peptide nucleic acids reverses `immortality' of transformed human cells

โœ Scribed by Shammas, Masood A; Simmons, Carla G; Corey, David R; Shmookler Reis, Robert J


Book ID
110062446
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
527 KB
Volume
18
Category
Article
ISSN
0950-9232

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## Abstract Human hepatocellular carcinoma (HCC) is one of the most common malignancies in Asia and Africa. Human telomerase reverse transcriptase (hTERT) is expressed in HCC but absent in normal human liver cells, which is consistent with the expression pattern of telomerase. In the present study,