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Potent Dipeptide Inhibitors of the pp60 c - src SH2 Domain

โœ Scribed by Pacofsky, Gregory J.; Lackey, Karen; Alligood, Krystal J.; Berman, Judd; Charifson, Paul S.; Crosby, Renae M.; Dorsey,, George F.; Feldman, Paul L.; Gilmer, Tona M.; Hummel, Conrad W.; Jordan, Steven R.; Mohr, Christopher; Shewchuk, Lisa M.; Sternbach, Daniel D.; Rodriguez, Marc


Book ID
118214299
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
244 KB
Volume
41
Category
Article
ISSN
0022-2623

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Highly Potent Inhibitors of the Grb2-SH2 Domain. -The preparation of peptide mimetics (IX) (11 examples) with different substituents at the 3-indolyl-propylamine C-terminal group and their inhibition of the Grb2-SH2 domain is reported.