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POTENT CARDIORENAL ANTIFIBROTIC EFFECTS OF THE RHO-KINASE INHIBITOR FASUDIL IN EXPERIMENTAL DIABETES MELLITUS.

✍ Scribed by Syed Ameenuddin; Elise A. Oehler; Josef Korinek; Jeson Sangaralingham; Alessandro Cataliotti; Fernando Martin; John A. Schirger; Horng H. Chen


Book ID
118579788
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
60 KB
Volume
55
Category
Article
ISSN
1558-3597

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✍ W. P. Chang; E. Dimitriadis; T. Allen; M. E. Dunlop; M. Cooper; R. G. Larkins πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 742 KB

The effect of two structurally unrelated aldose reductase inhibitors, sorbinil and ponalrestat, on glomerular prostaglandin production and urinary albumin excretion was investigated in rats with diabetes induced by streptozotocin. It was found that both aldose reductase inhibitors, when administered