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Preventive and therapeutic effects of the selective Rho-kinase inhibitor fasudil on experimental autoimmune neuritis

✍ Scribed by Arnold Angelo M. Pineda; Motozumi Minohara; Nobutoshi Kawamura; Takuya Matsushita; Ryo Yamasaki; Xiaojia Sun; Hua Piao; Hiroaki Shimokawa; Jun-ichi Kira


Book ID
119304055
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
946 KB
Volume
306
Category
Article
ISSN
0022-510X

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## Abstract The migration of aberrant inflammatory cells into the central nervous system plays an important role in the pathogenesis of demyelinating diseases potentially through the Rho/Rho‐kinase (Rock) pathway, but direct evidence from human and animal models remains inadequate. Here we further