๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Potent Antimalarial 1,2,4-Trioxanes through Perhydrolysis of Epoxides

โœ Scribed by Hao, Hong-Dong; Wittlin, Sergio; Wu, Yikang


Book ID
121274734
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
553 KB
Volume
19
Category
Article
ISSN
0947-6539

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Geraniol-derived 1,2,4-Trioxanes with po
โœ Chandan Singh; Nitin Gupta; Sunil K Puri ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 170 KB

Geraniol, an abundantly available naturally occurring allylic alcohol, has been used as a starting material to prepare a series of 6-[a-(3 0 -aryl-3 0 -hydroxypropyl)vinyl]-1,2,4-trioxanes. Some of these novel trioxanes have shown very promising antimalarial activity against multi-drug resistant Pla

Synthesis of New 1,2,4-Trioxanes and the
โœ Charles W. Jefford; Ernest C. McGoran; John Boukouvalas; Geoffrey Richardson; Br ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ German โš– 497 KB

The three dihydronaphtho[l,2,4]trioxines e l l have been synthesized and two of them converted to the five carbamate and ester derivatives 12-16 (Schemes I and 2). The resulting new trioxanes together with two already known and ascaridole (7) were tested for antimalarial activity against the sensiti

Olefin oxidative cleavage and dioxetane
โœ Gary H. Posner; Chang Ho Oh; Wilbur K. Milhous ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 316 KB

Oxidative cleavage of alkenyl esters and ethers using Et$iOOOH was found to be easier than oxidative cleavage of hydrocarbon alkenes, and Et3SiOOOH was successfully applied to very short syntheses of new, simple, and potent antimalarial trioxanes 6 and 8. We have reported recently that triethylsily