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Potassium channels: structures, models, simulations

✍ Scribed by Mark S.P. Sansom; Indira H. Shrivastava; Joanne N. Bright; John Tate; Charlotte E. Capener; Philip C. Biggin

Book ID
117048098
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
756 KB
Volume
1565
Category
Article
ISSN
0005-2736

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Potassium ion channels enable efficient and selective permeation of K + ions across nonpolar biological membranes. Here we review the results of recent free energy calculations related to the permeation of monovalent cations through K + channels and to the channel inhibition by blocker compounds. In