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Structural basis of TEA blockade in a model potassium channel

โœ Scribed by Lenaeus, Michael J; Vamvouka, Magdalini; Focia, Pamela J; Gross, Adrian

Book ID
109966968
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
725 KB
Volume
12
Category
Article
ISSN
1545-9993

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A topochemical model to explain the biological activity of dendrotoxin-I (DTX-I), a potent blocker for potassium channels, was developed by searching common spatial arrangements of functionally important residues between DTX-I, alpha-dendrotoxin, dendrotoxin-K, BgK, ShK, and charybdotoxin. The first