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Post-transcriptional regulation of P21WAF1/CIP1by P53

✍ Scribed by Jia-Fu Ji; Ji Zhang; Chun-Yu Jiao; Jin Gu; Li-Xin Tan; Ping Zhang; PeiXiang Li

Book ID
107466561
Publisher
Chinese Anti-Cancer Association
Year
2001
Tongue
English
Weight
438 KB
Volume
13
Category
Article
ISSN
1000-9604

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## Abstract Transforming growth factor‐β (TGF‐β) inhibits epithelial cell growth, in part via transcriptional induction of the cell cycle inhibitor p21^WAF1/Cip1^ (p21). We show that bone morphogenetic protein (BMP)‐7 induces higher p21 expression than TGF‐β1 in various epithelial cells. Despite th