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Possible role of dopamine D1 receptors in schizophrenia

✍ Scribed by Okuba, Y; Suhara, T; Sudo, Y; Toru, M


Book ID
110058806
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
32 KB
Volume
2
Category
Article
ISSN
1359-4184

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We studied the relationship between schizophrenia and the DdeI polymorphism in the 5 untranslated region (5UTR) of the dopamine D1 receptor (DRD1) gene. This polymorphism is an A (A1 allele) to G (A2 allele) transition in the 5 UTR of exon 2 at bp -48 (A-48G). One hundred forty-eight schizophrenics