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Possible Involvement of Interferon Regulatory Factor 4 (IRF4) in a Clinical Subtype of Adult T-Cell Leukemia

✍ Scribed by Imaizumi, Yoshitaka ;Kohno, Tomoko ;Yamada, Yasuaki ;Ikeda, Shuichi ;Tanaka, Yuetsu ;Tomonaga, Masao ;Matsuyama, Toshifumi

Book ID
108582074
Publisher
Wiley (Blackwell Publishing)
Year
2001
Tongue
English
Weight
273 KB
Volume
92
Category
Article
ISSN
0910-5050

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## Abstract ## BACKGROUND Active suppression by CD4^+^CD25^+^ regulatory T cells plays an important role in the down‐regulation of the response of T cells to foreign and self antigens. Experimental tumor models in mice revealed that regulatory T cells inhibit antitumor immune responses. The purpos