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Clinical significance of CADM1/TSLC1/IgSF4 expression in adult T-cell leukemia/lymphoma

✍ Scribed by Nakahata, S; Saito, Y; Marutsuka, K; Hidaka, T; Maeda, K; Hatakeyama, K; Shiraga, T; Goto, A; Takamatsu, N; Asada, Y; Utsunomiya, A; Okayama, A; Kubuki, Y; Shimoda, K; Ukai, Y; Kurosawa, G; Morishita, K

Book ID
121223578
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
648 KB
Volume
26
Category
Article
ISSN
0887-6924

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## Abstract Adult T‐cell leukemia/lymphoma (ATL) is a CD4^+^CD25^+^ T‐cell malignancy infected with human T‐cell leukemia virus type‐I (HTLV‐I). HTLV‐I infection causes the T‐cell dysfunction, which contributes to the immunodeficient state of the patients. Programmed death‐1 (PD‐1) can negatively r