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Possible importance of the HIV-1 mutations in vertical transmission and frequent anti retroviral drug resistance mutations in1 protease and reverse transcriptase genes in antiretroviral-naïve children

✍ Scribed by S. Hayakawa; D.Q. Trinh

Book ID: 113753794
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 75 KB
Volume: 94
Category: Article
ISSN: 0165-0378
DOI: 10.1016/j.jri.2012.03.486

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## Abstract This study aimed at identifying HIV‐1 protease amino acid changes associated with protease inhibitor (PI) exposure and susceptibility. New amino acid substitutions were correlated with the number of experienced PIs, reaching statistical significance only for those at positions 3, 44, an