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Positive role of mitogen-activated protein kinase phosphatase-1 in regulating the anti-mycobacterial immune responses

✍ Scribed by Benny K.W. Cheung; Howard C.H. Yim; Allan S.Y. Lau

Book ID
116398996
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
58 KB
Volume
48
Category
Article
ISSN
1043-4666

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## Abstract ## Objective Mitogen‐activated protein kinases (MAPKs) are activated by proinflammatory stimuli. MAPK phosphatases (MKPs), in particular MKP‐1, have been identified as endogenous negative regulators of MAPK activation. Since MAPKs are known to be important in rheumatoid arthritis (RA)