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161: Regulation of inflammatory response in enterocytes by transiently expressed mitogen-activated kinase phosphatase-1

✍ Scribed by A.V. Grishin; J. Wang; P. Boyle-Lockerbie; J.S. Upperman; H.R. Ford

Book ID
116702993
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
147 KB
Volume
137
Category
Article
ISSN
0022-4804

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## Abstract ## Objective Mitogen‐activated protein kinases (MAPKs) are activated by proinflammatory stimuli. MAPK phosphatases (MKPs), in particular MKP‐1, have been identified as endogenous negative regulators of MAPK activation. Since MAPKs are known to be important in rheumatoid arthritis (RA)