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Positional Cloning of the Werner's Syndrome Gene

โœ Scribed by Yu, C.-E.; Oshima, J.; Fu, Y.-H.; Wijsman, E. M.; Hisama, F.; Alisch, R.; Matthews, S.; Nakura, J.; Miki, T.; Ouais, S.; Martin, G. M.; Mulligan, J.; Schellenberg, G. D.

Book ID
121156041
Publisher
American Association for the Advancement of Science
Year
1996
Tongue
English
Weight
414 KB
Volume
272
Category
Article
ISSN
0036-8075

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## BACKGROUND: The curly tail (ct) mutant mouse is one of the best-studied mouse models of spina bifida. The ct mutation has been localized to distal chromosome 4 in two independent studies and was recently postulated to be in the Grhl-3 gene. METHODS: A recombinant BALB/c-ct strain was generated