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Positional cloning of the APECED gene

✍ Scribed by Antonarakis, Stylianos E.; Nagamine, Kentaro; Peterson, Pärt; Scott, Hamish S.; Kudoh, Jun; Minoshima, Shinsei; Heino, Maarit; Krohn, Kai J. E.; Lalioti, Maria D.; Mullis, Primus E.

Book ID
109918944
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
648 KB
Volume
17
Category
Article
ISSN
1061-4036

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## BACKGROUND: The curly tail (ct) mutant mouse is one of the best-studied mouse models of spina bifida. The ct mutation has been localized to distal chromosome 4 in two independent studies and was recently postulated to be in the Grhl-3 gene. METHODS: A recombinant BALB/c-ct strain was generated