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Porcine detrusor cyclic nucleotide phosphodiesterase isoenzymes: Characterization and functional effects of various phosphodiesterase inhibitors in vitro

✍ Scribed by Michael C. Truss; Rüdiger Hess; Stefan Ückert; Wolf-Georg Forssmann; Christian G. Stief; Udo Jonas; Peter Schulz-Knappe

Book ID: 119487785
Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 933 KB
Volume: 45
Category: Article
ISSN: 0090-4295
DOI: 10.1016/s0090-4295(99)80103-4

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The cyclic nucleotides cyclic adenosine monophosphate (CAMP) and cyclic guanosine monophosphate (cGMP) are second messengers involved in the regulation of contractility in various smooth muscle organs including detrusor smooth muscle. They are synthesized by activation of adenylate and guanylate cyc