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Cyclic Nucleotide Phosphodiesterase (PDE) Isoenzymes in the Human Detrusor Smooth Muscle: I. Identification and Characterization

✍ Scribed by Truss, M.C.; Uckert, S.; Stief, C.G.; Kuczyk, M.; Jonas, U.

Book ID
123411777
Publisher
Lippincott Williams and Wilkins
Year
1998
Tongue
English
Weight
236 KB
Volume
159
Category
Article
ISSN
0022-5347

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πŸ“œ SIMILAR VOLUMES

Cyclic nucleotide phosphodiesterase (PDE
Cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the human detrusor smooth muscle
✍ Truss, M. C. ;οΏ½ckert, S. ;Stief, C. G. ;Kuczyk, M. ;Jonas, U. πŸ“‚ Article πŸ“… 1996 πŸ› Springer 🌐 English βš– 575 KB

Phosphodiesterases (PDEs) are key enzymes involved in the regulation of intracellular cyclic nucleotide metabolism. The aim of the present study was to identify and to characterize the PDE isoenzymes present in the human detrusor smooth muscle. Human detrusor PDE isoenzymes were separated by Q-Sepha

Cyclic nucleotide phosphodiesterase (PDE
Cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the human detrusor smooth muscle
✍ Truss, M. C. ;οΏ½ckert, S. ;Stief, C. G. ;Forssmann, W. G. ;Jonas, U. πŸ“‚ Article πŸ“… 1996 πŸ› Springer 🌐 English βš– 585 KB

Phosphodiesterases (PDEs) regulate intracellular cyclic nucleotide metabolism and, thus, contraction and relaxation of smooth musculature. The aim of the present study was to evaluate the functional effects of isoenzyme-selective inhibitors and their effects on cyclic nucleotide levels in the human