Population stratification confounds genetic association studies among Latinos
✍ Scribed by Shweta Choudhry; Natasha E. Coyle; Hua Tang; Keyan Salari; Denise Lind; Suzanne L. Clark; Hui-Ju Tsai; Mariam Naqvi; Angie Phong; Ngim Ung; Henry Matallana; Pedro C. Avila; Jesus Casal; Alfonso Torres; Sylvette Nazario; Richard Castro; Natalie C. Battle; Eliseo J. Perez-Stable; Pui-Yan Kwok; Dean Sheppard; Mark D. Shriver; William Rodriguez-Cintron; Neil Risch; Elad Ziv; Esteban Gonzàlez Burchard; Genetics of Asthma in Latino Americans (GALA) Study
- Book ID
- 106134184
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 496 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0340-6717
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Genome‐wide case‐control association study is gaining popularity, thanks to the rapid development of modern genotyping technology. In such studies, population stratification is a potential concern especially when the number of study subjects is large as it can lead to seriously inflated
## Abstract Genome‐wide association studies are helping to dissect the etiology of complex diseases. Although case‐control association tests are generally more powerful than family‐based association tests, population stratification can lead to spurious disease‐marker association or mask a true asso