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Assessing the impact of population stratification on genetic association studies

✍ Scribed by Freedman, Matthew L; Reich, David; Penney, Kathryn L; McDonald, Gavin J; Mignault, Andre A; Patterson, Nick; Gabriel, Stacey B; Topol, Eric J; Smoller, Jordan W; Pato, Carlos N

Book ID
109918984
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
162 KB
Volume
36
Category
Article
ISSN
1061-4036

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## Abstract Genome‐wide case‐control association study is gaining popularity, thanks to the rapid development of modern genotyping technology. In such studies, population stratification is a potential concern especially when the number of study subjects is large as it can lead to seriously inflated