## Abstract Genomeโwide caseโcontrol association study is gaining popularity, thanks to the rapid development of modern genotyping technology. In such studies, population stratification is a potential concern especially when the number of study subjects is large as it can lead to seriously inflated
โฆ LIBER โฆ
New approaches to population stratification in genome-wide association studies
โ Scribed by Price, Alkes L.; Zaitlen, Noah A.; Reich, David; Patterson, Nick
- Book ID
- 109953225
- Publisher
- Nature Publishing Group
- Year
- 2010
- Tongue
- English
- Weight
- 523 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1471-0056
- DOI
- 10.1038/nrg2813
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## Abstract Hidden population substructure can cause population stratification and lead to falseโpositive findings in populationโbased genomeโwide association (GWA) studies. Given a large panel of markers scanned in a GWA study, it becomes increasingly feasible to uncover the hidden population subs
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