✦ LIBER ✦

Principal components analysis corrects for stratification in genome-wide association studies

✍ Scribed by Price, Alkes L; Patterson, Nick J; Plenge, Robert M; Weinblatt, Michael E; Shadick, Nancy A; Reich, David

Book ID: 109919406
Publisher: Nature Publishing Group
Year: 2006
Tongue: English
Weight: 199 KB
Volume: 38
Category: Article
ISSN: 1061-4036
DOI: 10.1038/ng1847

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Pathway-based analysis for genome-wide a

Pathway-based analysis for genome-wide association studies using supervised principal components

✍ Xi Chen; Lily Wang; Bo Hu; Mingsheng Guo; John Barnard; Xiaofeng Zhu 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 154 KB 👁 2 views

## Abstract Many complex diseases are influenced by genetic variations in multiple genes, each with only a small marginal effect on disease susceptibility. Pathway analysis, which identifies biological pathways associated with disease outcome, has become increasingly popular for genome‐wide associa

New approaches to population stratificat

New approaches to population stratification in genome-wide association studies

✍ Price, Alkes L.; Zaitlen, Noah A.; Reich, David; Patterson, Nick 📂 Article 📅 2010 🏛 Nature Publishing Group 🌐 English ⚖ 523 KB

Improved correction for population strat

Improved correction for population stratification in genome-wide association studies by identifying hidden population structures

✍ Qizhai Li; Kai Yu 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 433 KB 👁 1 views

## Abstract Hidden population substructure can cause population stratification and lead to false‐positive findings in population‐based genome‐wide association (GWA) studies. Given a large panel of markers scanned in a GWA study, it becomes increasingly feasible to uncover the hidden population subs

Testing for genetic association in the p

Testing for genetic association in the presence of population stratification in genome-wide association studies

✍ Kai Wang 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 449 KB 👁 2 views

## Abstract Genome‐wide case‐control association study is gaining popularity, thanks to the rapid development of modern genotyping technology. In such studies, population stratification is a potential concern especially when the number of study subjects is large as it can lead to seriously inflated

Meta-analysis of genome-wide association

Meta-analysis of genome-wide association studies for personality

✍ de Moor, M H M; Costa, P T; Terracciano, A; Krueger, R F; de Geus, E J C; Toshik 📂 Article 📅 2010 🏛 Nature Publishing Group 🌐 English ⚖ 577 KB

Variable set enrichment analysis in geno

Variable set enrichment analysis in genome-wide association studies

✍ Yang, Wei; de las Fuentes, Lisa; Dávila-Román, Victor G; Charles Gu, C 📂 Article 📅 2011 🏛 Nature Publishing Group 🌐 English ⚖ 581 KB