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Population pharmacokinetics of valproate in Chinese children with epilepsy

✍ Scribed by De-chun JIANG; Li WANG; Yu-qin WANG; Lin LI; Wei LU; Xiang-rong BAI


Book ID
111357120
Publisher
Nature Publishing Group
Year
2007
Tongue
Chinese
Weight
374 KB
Volume
28
Category
Article
ISSN
1671-4083

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Population pharmacokinetics of valproate
✍ Tania Correa; Ildefonso RodrΓ­guez; Silvia Romano πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 142 KB

## Abstract __Background__. The aim of this study was to determine the factors that influence valproate clearance (__CL__) in Mexican epileptic pediatric patients using a mixed‐effect model and sparse data of serum concentrations of valproic acid (VPA) collected during routine clinical care of pati