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Population pharmacokinetics of lamotrigine in Chinese children with epilepsy

✍ Scribed by He, Da-ke; Wang, Li; Qin, Jiong; Zhang, Shen; Lu, Wei; Li, Ling; Zhang, Jian-ming; Bao, Wei-qun; Song, Xiao-qing; Liu, Hai-tao


Book ID
120461368
Publisher
Nature Publishing Group
Year
2012
Tongue
Chinese
Weight
511 KB
Volume
33
Category
Article
ISSN
1671-4083

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## Abstract __Background__. The aim of this study was to determine the factors that influence valproate clearance (__CL__) in Mexican epileptic pediatric patients using a mixed‐effect model and sparse data of serum concentrations of valproic acid (VPA) collected during routine clinical care of pati