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Population pharmacokinetics of levetiracetam and dosing recommendation in children with epilepsy

✍ Scribed by Stephanie Chhun; Vincent Jullien; Elisabeth Rey; Olivier Dulac; Catherine Chiron; Gérard Pons


Book ID
109111126
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
291 KB
Volume
50
Category
Article
ISSN
0013-9580

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## Abstract __Background__. The aim of this study was to determine the factors that influence valproate clearance (__CL__) in Mexican epileptic pediatric patients using a mixed‐effect model and sparse data of serum concentrations of valproic acid (VPA) collected during routine clinical care of pati