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Population pharmacokinetics of halofantrine in healthy volunteers and patients with symptomatic falciparum malaria

โœ Scribed by Kerenaftali Klein; Leon Aarons; Feiko O. ter Kuile; Francois Nosten; Nick J. White; Michael D. Edstein; Paktiya Teja-Isavadharm


Book ID
119876933
Publisher
Pharmaceutical Press
Year
2012
Tongue
English
Weight
884 KB
Volume
64
Category
Article
ISSN
2042-7158

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Halofantrine is a new blood schizontocidal drug used for the treatment of multidrug-resistant falciparum malaria. The pharmacokinetics of halofantrine (HAL) and its principal metabolite, N-desbutylhalofantrine (BHAL), was investigated in 6 adult male patients of Melanesian origin with uncomplicated