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Pharmacokinetics of halofantrine in healthy Thai volunteers [letter]

โœ Scribed by J Karbwang; SA Ward; KA Milton; Na K Bangchang; G Edwards


Book ID
119833482
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
384 KB
Volume
32
Category
Article
ISSN
0306-5251

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Pharmacokinetics of an extended-dose hal
โœ Ohrt, Colin; Watt, George; Teja-Isavadharm, Paktiya; Keeratithakul, Duangsuda; L ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 811 KB

The pharmacokinetics and tolerance of a 4.5 gm 7&y halofantrine loading dose regimen were evaluated in 10 Thai patients with malaria and in 10 noninfected volunteers. Halofantrine peak plasma concentrations and bioavailability on the first day of treatment were significantly lower in patients with m