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Population pharmacokinetic modelling of the enterohepatic recirculation of diclofenac and rofecoxib in rats

✍ Scribed by D R H Huntjens; A Strougo; A Chain; A Metcalf; S Summerfield; D J M Spalding; M Danhof; O Della Pasqua


Book ID
110009897
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
359 KB
Volume
153
Category
Article
ISSN
0007-1188

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The pharmacokinetics of exaprolol and pr
✍ O. MotheovΓ‘; Ε . Bezek; M. ĎuriΕ‘ovΓ‘; V. FaberovΓ‘; M. ZemΓ‘nek; K. MiΕ‘Γ‘nikova; T. T πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 English βš– 509 KB

The pharmacokinetics of two beta adrenoceptor blocking drugs, exaprolol and propranolol, in rats with interrupted enterohepatic circulation was studied. The tritium-labelled drugs were given intravenously to four groups of rats: control, bile-duct cannulated, bile-duct ligated, and pretreated with n