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Population Pharmacokinetic Analysis of Istradefylline in Healthy Subjects and in Patients With Parkinson's Disease

โœ Scribed by Knebel, W.; Rao, N.; Uchimura, T.; Mori, A.; Fisher, J.; Gastonguay, M. R.; Chaikin, P.

Book ID
111949492
Publisher
Sage Publications
Year
2011
Tongue
English
Weight
532 KB
Volume
51
Category
Article
ISSN
0091-2700

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## Abstract The objective of this study was to evaluate the efficacy, safety, and tolerability of istradefylline 20 mg once daily versus placebo as an adjunct to levodopa in subjects with Parkinson's disease (PD) who have motor fluctuations. Istradefylline (KWโ€6002) is an adenosine A~2A~ receptor a