A long-term study of istradefylline in subjects with fluctuating Parkinson's disease
β Scribed by Stewart Factor; Margery H. Mark; Ray Watts; Lynn Struck; Akihisa Mori; Rocco Ballerini; Neil M. Sussman
- Book ID
- 116820766
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 164 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1353-8020
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## Abstract The objective of this study was to evaluate the efficacy, safety, and tolerability of istradefylline 20 mg once daily versus placebo as an adjunct to levodopa in subjects with Parkinson's disease (PD) who have motor fluctuations. Istradefylline (KWβ6002) is an adenosine A~2A~ receptor a
## Abstract Continuous subcutaneous apomorphine infusion (CSAI) is, at present, an alternative option for advanced Parkinson's disease (PD) with motor fluctuations. We studied the evolution of patients with PD and severe motor fluctuations longβterm treated with CSAI. We reviewed data from 82 patie