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Population pharmacokinetics of levodopa in patients with Parkinson's disease treated with tolcapone

✍ Scribed by Jorga, K


Book ID
111726780
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
66 KB
Volume
67
Category
Article
ISSN
0009-9236

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## Abstract Homocysteine, cysteine, and cysteinyl‐glycine are all metabolically interrelated. Levodopa/decarboxylase inhibitor (LD/DCI) administration increases total homocysteine (tHcy) plasma levels. Objectives were to investigate associations between LD/DCI intake, concentrations of tHcy, cystei

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## Abstract Dementia is a frequent non‐motor feature of Parkinson's disease (PD). Elevated plasma homocysteine (Hcy) levels have been associated with both cognitive impairment and dementia. Increased Hcy levels have been observed in levodopa‐treated patients with PD. The objective of our study was