Population genetics of Glutathione peroxidase (GPX1) in Central Portugal
β Scribed by M. Carvalho; A. Amorim
- Publisher
- Springer-Verlag
- Year
- 1998
- Tongue
- English
- Weight
- 109 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0393-9383
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Phenotype and allele frequencies for erythrocyte glutathione peroxidase (GPX1) polymorphism are reported in the Mbugu and Sango (Central African Republic), Goun (Benin), and Bamileke (Cameroon) ethnic groups. The GPX1\*2 allele frequencies (from 0.012 in the Sango to 0.058 in the Bamileke) fit into
Reactive oxygen species formation is strongly suspected to play a role in multistep carcinogenesis, notably in tumor promotion. The tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) induces peroxide production, oxidative damage to DNA and inflammation in mouse skin. TPA is also known to caus