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Population cytogenetics of folate-sensitive fragile sites

✍ Scribed by Marketta Kähkönen


Publisher
Springer
Year
1988
Tongue
English
Weight
458 KB
Volume
80
Category
Article
ISSN
0340-6717

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Chromosome fragile sites are inducible by aphidicolin in cultured human lymphocytes. To assess the frequency and distribution of these common fragile sites in the general population, a cytogenetic survey was performed on 126 subjects, 59 males and 67 females, whose age ranged from 1 day to 72 years.

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Population cytogenetic data on autosomal fragile sites show differences among different ethnic groups. The Basques are a n ancient population; their origin is not exactly known and many studies using several traits have shown peculiarities in the Basques. This is the first study about the incidence