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Cytogenetics of autosomal fragile sites: A Basque population study

✍ Scribed by M. I. Arrieta; E. Echarri; T. Nuñez; A. Gil; B. Criado; B. Martinez

Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
659 KB
Volume
8
Category
Article
ISSN
1042-0533

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✦ Synopsis

Population cytogenetic data on autosomal fragile sites show differences among different ethnic groups. The Basques are a n ancient population; their origin is not exactly known and many studies using several traits have shown peculiarities in the Basques. This is the first study about the incidence of autosomal fragile sites in a healthy Basque sample. The results show interindividual variability, no sex differences at a global level, but differences for some fragile sites. Compared with other populations, a higher incidence of rare autosomal fragile sites has been demonstrated (8%). o 1996 WiIey-Liss, Inc.

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✍ Bruna Tedeschi; Patrizia Vernole; M.Lucia Sanna; Benedetto Nicoletti 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 433 KB

Chromosome fragile sites are inducible by aphidicolin in cultured human lymphocytes. To assess the frequency and distribution of these common fragile sites in the general population, a cytogenetic survey was performed on 126 subjects, 59 males and 67 females, whose age ranged from 1 day to 72 years.