𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Poly[N-(2-hydroxypropyl)methacrylamide] conjugates of methotrexate: Synthesis and in vitro drug release

✍ Scribed by V. Šubr; J. Strohalm; T. Hirano; Y. Ito; K. Ulbrich


Book ID
114163303
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
518 KB
Volume
49
Category
Article
ISSN
0168-3659

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Synthesis and in vitro Characterization
✍ Jun H. Lee; Gauri Sabnis; Anjan Nan 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 349 KB

## Abstract Trastuzumab (TRZ) is a humanized monoclonal antibody that targets the extracellular domain of the human epidermal growth factor receptor type 2 (Her2). Semitelechelic (ST) poly[__N__‐(2‐hydroxypropyl)methacrylamide]–TRZ conjugates are successfully synthesized and evaluated as a potentia

Synthesis and Characterization of Poly(ε
✍ Stefan G. Krimmer; Huaizhong Pan; Jihua Liu; Jiyuan Yang; Jindřich Kopeček 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 747 KB

## Abstract Amphiphilic block copolymers based on HPMA and ε‐CL were synthesized by ring‐opening polymerization of ε‐CL followed by RAFT polymerization of HPMA. A copolymer composed of 34 kDa PHPMA and 8.5 kDa PCL associated into micelles with CMC of 5.4 µg · mL^−1^. A novel retinoid, 3‐Cl‐AHPC‐OMe

Release of Prostaglandin E1 from N-(2-Hy
✍ Huaizhong Pan; Jihua Liu; Yuanyi Dong; Monika Sima; Pavla Kopečková; Maria Luisa 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 252 KB

## Abstract Bone‐targeting __N__‐(2‐hydroxypropyl)methacrylamide (HPMA) copolymer‐PGE~1~ conjugates, containing cathepsin K sensitive spacers, were incubated with induced osteoclasts and osteoblasts, their precursors, and control non‐skeletal cells. The release of PGE~1~ was monitored by an HPLC as