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Polymorphisms within a polymorphism: SNPs in and around a polymorphicAluinsertion in intron 44 of the human dystrophin gene

✍ Scribed by AlanD. Lovell; Vania Yotova; Fengxia Xiao; MarkA. Batzer; Damian Labuda

Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
276 KB
Volume
49
Category
Article
ISSN
1435-232X

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A 300-bp EcoRV polymorphism, detected with P20 (DXS269) in intron 44 of the human dystrophin gene, is due to an insertion or deletion. To make this restriction fragment length polymorphism (RFLP) available for polymerase chain reaction (PCR) analysis, we sequenced both alleles of this polymorphism a

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The genetic polymorphism of an entire Bov‐A2 element located in the second intron of the buffalo and bovine k‐casein (__CSN3__) gene was investigated by amplification and sequencing of PCR products. Single nucleotide polymorphisms were detected. A PCR‐RFLP method was developed to detect an A or G mu