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Polymorphisms inGSTT1,GSTM1,NAT1andNAT2genes and bladder cancer risk in men and women

✍ Scribed by Monica McGrath; Dominique Michaud; Immaculata De Vivo

Book ID
115010874
Publisher
BioMed Central
Year
2006
Tongue
English
Weight
289 KB
Volume
6
Category
Article
ISSN
1471-2407

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## Abstract Isothiocyanates (ITCs) are nonnutrient compounds in cruciferous vegetables with anticarcinogenic properties. ITCs down‐regulate cytochrome P‐450 biotransformation enzyme levels, activate Phase II detoxifying enzymes and induce apoptosis. On the other hand, ITCs also serve as a substrate