𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Polymorphisms in TP53 and MDM2 combined are associated with high grade endometrial cancer

✍ Scribed by Katie A. Ashton; Anthony Proietto; Geoffrey Otton; Ian Symonds; Mark McEvoy; John Attia; Michael Gilbert; Ute Hamann; Rodney J. Scott


Book ID
113961942
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
523 KB
Volume
113
Category
Article
ISSN
0090-8258

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Genetic polymorphisms in cell cycle regu
✍ Xuemei Zhang; Xiaoping Miao; Yongli Guo; Wen Tan; Yifeng Zhou; Tong Sun; Yonggan πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 226 KB

The tumor suppressor TP53 pathway plays a crucial role in preventing carcinogenesis through its ability to impose cell cycle arrest and apoptosis following DNA damage and oncogene activation. MDM2 is a key negative regulator of the TP53 pathway and is overexpressed in many cancers as oncoprotein. We