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Polymorphisms in the DNA repair genes XRCC1, APEX1, XRCC3 and NBS1, and the risk for lung cancer in never- and ever-smokers

โœ Scribed by Ryk, Charlotta; Kumar, Rajiv; Thirumaran, Ranjit K.; Hou, Sai-Mei


Book ID
119319478
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
164 KB
Volume
54
Category
Article
ISSN
0169-5002

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## Abstract The etiology of lung cancer in population with little or no tobacco exposure is not well understood. Individual genetic susceptibility factors have been suggested to contribute to lung cancer risk in this population. Mutations in the p53 tumor suppressor gene are implicated in the devel