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Polymorphisms in hypoxia inducible factor 1 and the initial clinical presentation of coronary disease

✍ Scribed by Mark A. Hlatky; Thomas Quertermous; Derek B. Boothroyd; James R. Priest; Alec J. Glassford; Richard M. Myers; Stephen P. Fortmann; Carlos Iribarren; Holly K. Tabor; Themistocles L. Assimes; Robert J. Tibshirani; Alan S. Go

Book ID
116191133
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
174 KB
Volume
154
Category
Article
ISSN
1097-6744

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## Abstract With an incidence of about 300 000 new cases colorectal cancer (CRC) is the second leading cause of cancer‐related death in Europe and the United States. Environmental and genetic factors influence CRC risk. Hypoxia‐inducible factor‐1 (HIF‐1), a heterodimeric protein composed of two sub